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A Comparative Study among Intravenous Lignocaine, 2% Lignocaine Nebulisation and 4% Lignocaine Nebulisation in blunting of Laryngeal Response during Intubation, randomised clinical trial

Not Applicable
Conditions
Health Condition 1: R688- Other general symptoms and signs
Registration Number
CTRI/2021/09/036202
Lead Sponsor
Pondicherry Institute of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1)Patients aged between 18 and 60 yrs.

2)American Society of Anaesthesiologists ASA 1 and ASA 2 patients coming for GA.

3)Patients coming for elective procedures.

Exclusion Criteria

1) Surgery involving the oral, nasopharyngeal, laryngotracheal airway or thyroid.

2) Patients history of respiratory disease (COPD, asthma).

3) History of recent respiratory tract infection.

4) Patients with anticipated difficult intubation and

Those requiring > 3 attempts at laryngoscopy and intubation.

5) History of any known allergy to Lignocaine.

6) Patients coming for emergency procedures.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Primary objective: To compare hemodynamic responses to Intubation in topical <br/ ><br>2% lignocaine and 4% lignocaine patients and compare it with intravenous lignocaine <br/ ><br> in patients undergoing General anaesthesia. <br/ ><br>Timepoint: Baseline, 1min, 2min, 3min, 4min, 5min, 10min.
Secondary Outcome Measures
NameTimeMethod
To study any adverse drug reactionsTimepoint: 1min, 2min, 3min, 4min, 5min, 10min
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