A nutrition and lifestyle intervention in patients with PuLmonary Arterial Hypertension: effect on quality of life

Recruiting

Conditions: high blood pressure in the pulmonary arteriole
Pumonary Arterial Hypertension
10019280
10037454

Registration Number: NL-OMON48646

Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 70

Inclusion Criteria

Diagnoses of idiopathic PAH, hereditary PAH or drug related PAH
Age between 18 and 80
NYHA II or III and stable for at least three months, measured with 6MWT <10%
differnce
Self-sufficient and/or compliance from partner and/or family
Creatinine > 30 ml/min
Able to understand and willing to sign the Informed Consent Form

Exclusion Criteria

Pregnant subjects
Fat percentage < 10% > 55%
One or more of the following comorbidities: diabetes mellitus type one or two,
clinical relevant hypothyroid
Known history of noncompliance considering therapies

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To explore the effect of a nutrition and lifestyle intervention for<br /><br>PAH-patients on quality of life. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Perform a systematic analyses of nutritional status. Is nutritional status<br /><br>associated with clinical worsening or RV function in PAH?<br /><br>- Determine the effect of nutritional education alone, and the additional<br /><br>effect of a nutritional intervention in PAH.<br /><br>- Determine which nutritional intervention is most effective. Which diet is<br /><br>associated with the largest improvement in quality of life and best compliance<br /><br>in PAH?</p><br>