Complex Problem Solving Training in Schizophrenic Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 91
- 试验地点
- 1
- 主要终点
- Functional Capacity as assessed by Osnabrücker Arbeitsfähigkeitsprofil "learning ability" subscale
研究概览
简要总结
The primary purpose of the study is to assess whether a planning and problem-solving training is more effective in improving work therapy performance in patients with schizophrenia than traditional training programs addressing basic cognitive functions.
详细描述
In patients with schizophrenia, cognitive deficits often lead to an impairment in daily life. This observation has led to the development of cognitive training packages aiming a improving these deficits. However, it is far from clear which level of cognitive functioning provides the best target for cognitive interventions. Traditionally, training has aimed a basic cognitive functions like attention and memory. In the present study we aim at a higher-level of function, namely planning and problem-solving skills, which are trained using the software package Plan-A-Day. The primary hypothesis is that complex problem solving training improved functional capacity more than traditional training programs addressing basic cognitive function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with schizophrenic or schizoaffective Disorder (DSM IV)
- •Remitted positive symptoms (PANSS positive all ≤ 4), clinical stability
- •Native German speaker
- •Verbal IQ > 80
- •Visual acuity normal or corrected to normal
排除标准
- •Concurrent Axis-I disorder
- •Drug abuse during last 2 months
- •Neurological or medical conditions potentially affecting cognition
研究组 & 干预措施
A
Complex Problem Solving Training
干预措施: Complex Problem Solving Training (Behavioral)
B
Basic Cognitive Training
干预措施: Basic Cognitive Training (Behavioral)
结局指标
主要结局
Functional Capacity as assessed by Osnabrücker Arbeitsfähigkeitsprofil "learning ability" subscale
时间窗: 3 weeks
次要结局
- Functional Capacity as assessed by the Osnabrücker-Arbeitsfähigkeitsprofil summary score(3 weeks)
- BADS Zoo Map Score (Neuropsychological Test)(3 weeks)
- Planungstest (Tower of London) Summary Score (Neuropsychological Test)(3 weeks)
- Plan-A-Day S Solution Time (Neuropsychological Test)(3 weeks)