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Validation of 99mTc- EDDA - HYNIC -TOC Kits for Diagnosis of Neuroendocrine Tumors

Phase 2
Completed
Conditions
Neuroendocrine Tumors
Interventions
Other: 99m Tc - HYNIC -TOC EDDA and 111In - DTPA-octreotide
Registration Number
NCT02691078
Lead Sponsor
Latin American Cooperative Oncology Group
Brief Summary

Evaluation of the properties of the image capture test using 99m Tc - HYNIC -TOC EDDA (octreotide labeled with 99mTc) for the diagnosis of neuroendocrine tumors compared to the 111In - DTPA-octreotide.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
15
Inclusion Criteria
  • Patients with histological diagnosis of neuroendocrine tumors
  • Patients with indication for the staging exam with 11In
  • Patients diagnosed in any tumor stage
  • Patients with > 18 years
  • Male and female patients
  • Patients not receiving somatostatin analogues for at least 1 month before image capturing
Exclusion Criteria
  • Pregnant women
  • Patients with previous tumor resection of the primary tumor without metastatic disease

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Adult patients with neuroendocrine tumors99m Tc - HYNIC -TOC EDDA and 111In - DTPA-octreotide-
Primary Outcome Measures
NameTimeMethod
Analysis of the images captured with 99m Tc - HYNIC -TOC EDDA ( octreotide labeled with 99mTc ) and 111In - DTPA-octreotide for the diagnosis of neurocrine tumorsUp to 30 days
Secondary Outcome Measures
NameTimeMethod
Visualization of the ocurrence of the neuroendocrine tumor lesions with both radiopharmaceutical agentsUp to 30 days
Number of neuroendocrine tumor lesions visualized with both radiopharmaceutical agentsUp to 30 days

Trial Locations

Locations (1)

Instituto do Cérebro do Rio Grande do Sul

🇧🇷

Porto Alegre, Rio Grande Do Sul, Brazil

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