Evaluation of Antibiotherapy Prescribed for Outpatients From Emergency Departments

• Conditions: Infectious Disease; Emergencies

• Registration Number: NCT05350995
• Lead Sponsor: Henri Mondor University Hospital

Brief Summary

French health insurance data indicate that approximately 15% of ambulatory antibiotic consumption is generated by hospital prescriptions. This extra-hospital consumption represents a greater volume than intra-hospital consumption. To date, hospital indicators of good antibiotic use do not include this outpatient dimension. This study will provide a snapshot of the proportion of ambulatory antibiotics generated by emergencies and analyze compliance with management recommendations.This study will serve as a basis for developing indicators of outpatient antibiotic consumption generated by hospital activity and for identifying specific intervention targets aimed at the misuse situations that have been highlighted.

This study will be carried out in the form of a repeated survey on a given day (4 days, one across each season), carried out by the local mobile antibiotic therapy team, using a standardized grid. The survey will concern all the medical records of the patients visiting any emergency department on the days of the survey.

The evaluation of antibiotic therapies prescribed in discharge orders will be carried out in accordance with local management recommendations by the site investigator (infectious disease and/or emergency medicine specialist), who will assess whether the prescription is in accordance with the recommendations or not.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-03-15
• Study First Submitted QC: 2022-04-27
• Study First Posted: 2022-04-28
• Study Start: 2022-05-13
• Status Verified: 2022-08
• Last Update Submitted: 2022-08-02
• Last Update Posted: 2022-08-04
• Primary Completion: 2023-04-01
• Study Completion: 2023-04-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 9600

Inclusion Criteria

• Visit on emergency department on one of the survey days
• Age ≥18

Exclusion Criteria

• Patient opposed to the collection of his/her data
• Patient under guardianship or curatorship

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Adequacy to local or national recommendations of antibiotic prescriptions identified on patient discharge prescriptions after a visit in emergency departments.	through study completion, an average of 1 year	Adequacy to local or national recommendations (adequate/not adequate) of prescriptions, assessed by local investigator (infectious disease and/or emergency medicine specialist) at 4 days of collection: 1 day in each season (spring, summer, autumn and winter).

Secondary Outcome Measures

Name	Time	Method
Adequacy to the local or national recommendations of the antibiotic prescriptions identified on the patient discharge prescriptions by diagnosis.	Through study completion, an average of 1 year	Adequacy to local or national recommendations (adequate/not adequate) of the antibiotic prescriptions identified on the patient discharge prescriptions by diagnosis assessed at 4 days of collection: 1 day in each season (spring, summer, autumn and winter).
Antibiotics prescription rate at discharge from emergency department.	Through study completion, an average of 1 year
Factors associated with inadequacy to the local or national recommendations.	Through study completion, an average of 1 year
Critical antibiotics prescription rate at discharge from emergency department.	Through study completion, an average of 1 year	Critical antibiotics are defined by ANSM guidelines.

Trial Locations

Locations (1)

CHU Henri Mondor; 🇫🇷 Créteil, France