Gastric Cancer and Helicobacter Pylori Infection in Lima, Peru: The Role of Water Contamination
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- SWOG Cancer Research Network
- Enrollment
- 107
- Locations
- 1
- Primary Endpoint
- Detect H. pylori in public drinking water of Lima Peru
Study Overview
Brief Summary
The objective of this study is to elucidate the role of drinking water derived from the public source in Lima, Peru and transmission of H. pylori infection using genotypic techniques.
Detailed Description
The objective of this study is to detect the presence of Helicobacter Pylori in the drinking water derived from the public network by molecular and genomic techniques in districts of Lima (Brena, Chorrillos, Comas, El Agustino, La Victoria, Lince, Los Olivos, Miraflores, Puente Piedra, Rimac, San Isidro, San Juan de Lurigancho, San Martin de Porres, Villa El Salvador, and Villa Maria del Triunfo) with high and low incidence of gastric carcinoma. The secondary objective of this study is to establish correlations between the findings in water and those of the stomach of patients with symptoms of dyspepsia who live in those districts.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 21 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •adults between the ages of 21-70 years old who have lived for more than 10 years in the Lima districts listed in protocol,
- •who have a biopsy proven diagnosis of infection by H. pylori.
- •participants must be in good general condition, mentally competent and able to provide informed consent;
- •must not show evidence of dehydration or jaundice;
- •must be willing to complete the patient questionnaires.
- •participants must not have known allergies to any of the antibiotics used in the study.
Exclusion Criteria
- •pregnancy
Outcomes
Primary Outcomes
Detect H. pylori in public drinking water of Lima Peru
Time Frame: within 1 year of receving last sample
To detect the presence of Helicobacter Pylori (H. pylori) in the drinking water derived from the public network by molecular and genomic techniques in districts of Lima, Peru (districts detailed in protocol).
Secondary Outcomes
- Correlation of H. pylori in water and those of stomachs of patients with symptoms(Within 1 year of receiving last sample)