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Clinical Trials/NCT02024022
NCT02024022
Completed
Phase 4

A Comparison of Bowel Prep Quality and Patient Satisfaction in Outpatients Undergoing Colonoscopy Preparation With Either a Standard Bowel Preparation or an Individualized Approach Using Sodium Picosulphatge/Magnesium Citrate or 4L Polyethylene Glycol Preparation Regimens

Clinical Hospital Colentina3 sites in 1 country185 target enrollmentFebruary 2014

Overview

Phase
Phase 4
Intervention
Standard approach
Conditions
Bowel Cleansing Process
Sponsor
Clinical Hospital Colentina
Enrollment
185
Locations
3
Primary Endpoint
bowel cleansing
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

This study aims to compare a standard approach to bowel preparation for colonoscopy (using sodium picosulphate/magnesium citrate or 4lPEG) to an individualized approach where patients are assigned a specific regimen of either sodium picosulphate/magnesium citrate or 4lPEG depending on patient-related factors. The study aims to compare patient-related outcomes such as comfort levels during bowel cleansing and physician-related outcomes such as bowel prep quality in the two study groups.

Registry
clinicaltrials.gov
Start Date
February 2014
End Date
December 2015
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Clinical Hospital Colentina
Responsible Party
Principal Investigator
Principal Investigator

dr. Theodor Alexandru Voiosu

MD, gastroenterology resident

Clinical Hospital Colentina

Eligibility Criteria

Inclusion Criteria

  • all patients \> 18 years of age undergoing elective colonoscopy on an outpatient basis

Exclusion Criteria

  • refusal to sign informed consent
  • pregnancy
  • advance kidney, liver or heart disease
  • suspicion of malignant / benign stenosis of the digestive tract

Arms & Interventions

Standard approach

patients will be randomized to one of the 2 currently used bowel preparation regimens in our clinic: * 4L split polyethylene glycol solution * split magnesium citrate/sodium picosulphate preparation regimen

Intervention: Standard approach

Individualized approach

patients will receive either the 4L split polyethylene glycol bowel prep regimen or the sodium picosulphate/magnesium citrate split prep regimen according to personal characteristics assessed using a self-administered questionnaire (including bowel habits, the preference for large-volume preparation and education level)

Intervention: Individualized approach

Outcomes

Primary Outcomes

bowel cleansing

Time Frame: 24 hours

bowel cleansing as assessed during colonoscopy using 2 assessment scales (Boston bowel prep scale, and a 1-4 semiquantitative scale)

Secondary Outcomes

  • patient comfort level during bowel cleansing(24 hours)

Study Sites (3)

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