Intensive prolonged exposure therapy for posttraumatic stress disorder in patients with a psychotic disorder: a single trial desig
- Conditions
- (1) PTSD (2) trauma10002861
- Registration Number
- NL-OMON51923
- Lead Sponsor
- ProPersona (Nijmegen)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 10
In order to be eligible to participate in this study, a subject must meet all
of the following criteria:
1) a minimum age of 18 years;
2) a diagnosis of PTSD that meets the criteria of the DSM-5 (American
Psychiatric Association, 2013) measured with the Clinician-Administered PTSD
Scale (CAPS-5; Weathers, Keane, & Davidson, 2001; Weathers, et al., 2018) and;
3) a co-morbid current diagnosis of a psychotic disorder according to the
Mini-International Neuropsychiatric Interview-S (MINI-S) (Sheehan, et al.,
1998)
A potential subject who meets any of the following criteria will be excluded
from participation in this study:
1) high acute suicide risk, characterized as a suicide attempt within the past
2 months;
2) changes in antipsychotic or antidepressant medication within two months
before the start of this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main outcome is self-rated changes in severity of PTSD symptoms on the PTSD<br /><br>checklist for DSM 5 (PCL-5) and clinician-rated PTSD symptoms and diagnosis<br /><br>measured with the Clinician-Administered PTSD Scale (CAPS-5). </p><br>
- Secondary Outcome Measures
Name Time Method