The Early Therapeutic Efficacy of The Robot-Assisted Laparoscopic Radical Prostatectomy Combined Anterior and Posterior Approach: A Single-Center Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 233
- 试验地点
- 1
- 主要终点
- urinary continence
研究概览
简要总结
The goal of this observational study was to compare the perioperative outcomes, postoperative urinary control rates and positive surgical margin (PSM) rates of the robot-assisted laparoscopic radical prostatectomy combined anterior and posterior approach (AP-RARP) with the Retzius-sparing approach (RS-RARP) and anterior approach (anterior-RARP) in the treatment of prostate cancer. The main question it aims to answer was:
• The early therapeutic efficacy of the robot-assisted laparoscopic radical prostatectomy combined anterior and posterior approach
Participants has been underwent:
- AP-RARP
- RS-RARP
- anterior-RARP Researchers compared the three groups to see if AP-RARP combines the advantages of anterior and posterior RARP and is a feasible surgical option for the treatment of prostate cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •pathologically diagnosed with prostate cancer by prostate biopsy
- •underwent robot-assisted laparoscopic surgery
- •the surgery performed by Weidong Gan
- •the extended pelvic lymphadenectomy (PLA) is performed on patients with high-risk prostate cancer (PSA≥20 ng/ml or Grade Group 4-5 or clinical stage ≥T2c) and those considered to have a possibility of lymph node metastasis based on imaging evaluation.
排除标准
- •Patients with a clinical and pathological TNM stage ≥T3b and N1
- •patients with distant metastasis
- •urinary incontinence before surgery
- •received neoadjuvant therapy before surgery
结局指标
主要结局
urinary continence
时间窗: 0-6 month after surgery
was defined as using 0-1 pad a day
positive surgical margin
时间窗: 2 weeks after surgery
observed whether the tissue cutting in surgery has tumor cell in surgical margin by pathologist
次要结局
- operating time(the day of the surgery)
- intraoperative blood loss(the day of the surgery)
研究者
Fan Feng
Attending Doctor
Nanjing University School of Medicine