Comparison of Robot-assisted Donornephrectomy vs Hand-assisted Laparoscopic Donornephrectomy

Completed

• Conditions: Robotic Surgery; Kidney Donation
• Interventions: Procedure: Robotic surgery

• Registration Number: NCT05194280
• Lead Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Brief Summary

The aim of this retrospective study was to analyze donor and recipient outcomes after robotic-assisted donor nephrectomy and hand-assisted laparoscopic donornephrectomy.

Detailed Description

Living donor kidney transplantation is superior to cadaveric kidney transplantation because of the better patient and graft survival rates, better cost-effectiveness and improved quality of life of the recipient. According to the current guidelines, the laparoscopic technique of donor nephrectomy is now recommended as "the preferential technique". The advantages of the hand-assisted laparoscopic donor nephrectomy (HALDN) as compared with the conventional laparoscopy include tactile feedback, less kidney traction, rapid kidney removal and a shorter warm ischemic period. HALDN is nowadays the most frequently used technique in the U.S. for living donor nephrectomy. The laparoscopic techniques may have helped to increase the expansion of the donor pool. However, laparoscopic surgery have some disadvantages especially ergonomic inconveniences for the surgeon, which may result in decreased surgeons' performance and musculoskeletal disorders. Surgical robotics can play a role in extending surgical careers, by allowing surgeons to perform high volume laparoscopic surgery in a more ergonomic way. Robotic assistance in living donor nephrectomy can offer improved safety by enhanced control, accuracy, stability, and vision. The aim of this retrospective study was to compare the robotic assisted donor nephrectomy (RADN) with the HALDN technique with respect to donor and recipient outcomes.

Study Timeline

• Study Start: 2017-03-01
• Primary Completion: 2021-03-30
• Study Completion: 2021-10-20
• Study First Submitted: 2021-12-18
• Status Verified: 2022-01
• Study First Submitted QC: 2022-01-14
• Last Update Submitted: 2022-01-14
• Study First Posted: 2022-01-18
• Last Update Posted: 2022-01-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 186

Inclusion Criteria

• Adult, healthy condition

Exclusion Criteria

• Children, not suitable for kidney donation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Robotic-assisted group	Robotic surgery	Group of patients that underwent a robotic-assisted donornephrectomy

Primary Outcome Measures

Name	Time	Method
Post-operative pain score	0-3 days	Visual Analogue Scale was used to measure the postoperative pain. From the operation date till discharge from the hospital

Secondary Outcome Measures

Name	Time	Method
Operating time	30-300 min	Operating time in minutes

Trial Locations

Locations (1)

Amsterdam UMC, location AMC; 🇳🇱 Amsterdam, Netherlands