Long-term Renal Outcome After Cardiac Surgery : Impact of Previous Renal Transplantation
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiac Surgery
- Sponsor
- University Hospital, Bordeaux
- Enrollment
- 93
- Locations
- 1
- Primary Endpoint
- Long-term renal outcome
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
In this retrospective study, the authors assess long term renal outcome in renal transplant recipients after cardiac surgery with cardiopulmonary bypass, and research factors associated with poor long term renal outcome.
Detailed Description
Post-operative mortality after cardiac surgery is increased in renal transplant recipients, compared with general population of cardiac surgery, or with kidney transplant recipients not undergoing cardiac surgery. If the survival of this specific population is now well studied, the long-term renal outcome is much less studied. Previous studies show a trend for increased risk of allograft dysfunction and need for permanent dialysis. This study proposes to compare long term renal outcome between renal transplant recipients and non-renal transplant recipients.
Investigators
Alexandre Ouattara
MD, PhD
University Hospital, Bordeaux
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Patients requiring mechanical circulatory support (Extracorporeal Membrane Oxygenation)
- •Pre-operative permanent dialysis
- •Aorta dissection extended to renal arteries
- •Non-elective surgery for infective endocarditis
- •Previous hepatic, pancreatic or cardiac transplantation
- •Death in the 30 first days after cardiac surgery
- •Patient not meeting the inclusion criteria
Outcomes
Primary Outcomes
Long-term renal outcome
Time Frame: 12 months after surgery
Proportion of patients meeting a composite criterion : death or permanent dialysis or doubling the baseline serum creatinine value
Secondary Outcomes
- Vital status(12 months after surgery)
- Glomerular Filtration Rate (GFR)(12 months after surgery)
- Major Adverse Kidney Events(Up to 12 months after surgery)