Long-term Renal Outcome After Cardiac Surgery : Impact of Previous Renal Transplantation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- Long-term renal outcome
研究概览
简要总结
In this retrospective study, the authors assess long term renal outcome in renal transplant recipients after cardiac surgery with cardiopulmonary bypass, and research factors associated with poor long term renal outcome.
详细描述
Post-operative mortality after cardiac surgery is increased in renal transplant recipients, compared with general population of cardiac surgery, or with kidney transplant recipients not undergoing cardiac surgery. If the survival of this specific population is now well studied, the long-term renal outcome is much less studied. Previous studies show a trend for increased risk of allograft dysfunction and need for permanent dialysis. This study proposes to compare long term renal outcome between renal transplant recipients and non-renal transplant recipients.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •Patients requiring mechanical circulatory support (Extracorporeal Membrane Oxygenation)
- •Pre-operative permanent dialysis
- •Aorta dissection extended to renal arteries
- •Non-elective surgery for infective endocarditis
- •Previous hepatic, pancreatic or cardiac transplantation
- •Death in the 30 first days after cardiac surgery
- •Patient not meeting the inclusion criteria
结局指标
主要结局
Long-term renal outcome
时间窗: 12 months after surgery
Proportion of patients meeting a composite criterion : death or permanent dialysis or doubling the baseline serum creatinine value
次要结局
- Vital status(12 months after surgery)
- Glomerular Filtration Rate (GFR)(12 months after surgery)
- Major Adverse Kidney Events(Up to 12 months after surgery)
研究者
Alexandre Ouattara
MD, PhD
University Hospital, Bordeaux