Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery
- Conditions
- Anastomotic LeakGastric Cancer
- Interventions
- Biological: Human albumin
- Registration Number
- NCT04490668
- Lead Sponsor
- Ruijin Hospital
- Brief Summary
We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.
- Detailed Description
Anastomotic leakage after gastric cancer surgery is not very common but it is a very critical postoperative complication. Anastomotic leakage severely compromises the recovery after surgery. It increases the overall burden of patients and hospital resources. Postoperative mortality is higher in patients with anastomotic leakage.
Human albumin is routinely administered after surgery with a unproven hypothesis that the human albumin is beneficial to prevent anastomotic leakage. We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1049
- Histologically confirmed gastric cancer
- Patients who underwent radical gastrectomy
- Patient who did not undergo gastrectomy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description No human albumin support Human albumin Patients who did not receive intravenous human albumin after gastric cancer surgery Human albumin support Human albumin Patients who received intravenous human albumin after gastric cancer surgery
- Primary Outcome Measures
Name Time Method Comparison of the rate of anastomotic leakage Up to one months after the discharge of last patient The rate of anastomotic leakage were compared among both groups
- Secondary Outcome Measures
Name Time Method