Association of Human Albumin With Anastomotic Leakage After Gastric Cancer Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,049
- 主要终点
- Comparison of the rate of anastomotic leakage
研究概览
简要总结
We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.
详细描述
Anastomotic leakage after gastric cancer surgery is not very common but it is a very critical postoperative complication. Anastomotic leakage severely compromises the recovery after surgery. It increases the overall burden of patients and hospital resources. Postoperative mortality is higher in patients with anastomotic leakage.
Human albumin is routinely administered after surgery with a unproven hypothesis that the human albumin is beneficial to prevent anastomotic leakage. We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically confirmed gastric cancer
- •Patients who underwent radical gastrectomy
排除标准
- •Patient who did not undergo gastrectomy
结局指标
主要结局
Comparison of the rate of anastomotic leakage
时间窗: Up to one months after the discharge of last patient
The rate of anastomotic leakage were compared among both groups
次要结局
未报告次要终点
研究者
BIRENDRA KUMAR SAH
Principal investigator
Ruijin Hospital