The Effect of Inhalation Agent on the QTc Interval During Liver Transplantation: Sub Study (NCT01886664)
- Registration Number
- NCT01899248
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
The purpose of this study is to assess the effects of inhalation agent on corrected QT interval duration during liver transplantation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
- elective liver transplantation
Exclusion Criteria
- age < 18, age > 65
- patient refusal
- re-transplantation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Sevoflurane Sevoflurane Performing liver transplantation under general anesthesia using sevoflurane Desflurane Desflurane Performing liver transplantation under general anesthesia using desflurane
- Primary Outcome Measures
Name Time Method corrected QT interval (QTc interval) up to postoperative day 1 after surgery up to 10 minutes after tracheal intubation, up to 60 minutes after reperfusion, at 10 minutes after hepatectomy, at 10 minutes after biliary anastomosis, at skin closure, at the arrival on ICU, on postoperative day 1.
- Secondary Outcome Measures
Name Time Method proportion of patients whose QTc interval is more than 450 ms for men and 470 ms for women up to postoperative day 1 after surgery proportion of patients who have more than 500 ms of QTc interval up to postoperative day 1 after surgery Tp-e interval up to postoperative day 1 after surgery up to 10 minutes after tracheal intubation, up to 60 minutes after reperfusion, at 10 minutes after hepatectomy, at 10 minutes after biliary anastomosis, at skin closure, at the arrival on ICU, on postoperative day 1.
Trial Locations
- Locations (1)
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of