CAMELOT - Continuous rectus sheath Analgesia in eMErgency LaparOTomy

Not Applicable

Active, not recruiting

• Conditions: se of rectus sheath catheters (RSCs) in patients undergoing emergency bowel surgery.; Surgery

• Registration Number: ISRCTN15475290
• Lead Sponsor: niversity Hospital Southampton NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-08-09
• Last Update Posted: 18 September 2023
• Study Completion: 2026-10-26

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 750

Inclusion Criteria

1. Aged =18 years
2. Undergoing emergency laparotomy surgery via a midline incision
3. Eligible for inclusion in the National Emergency Laparotomy Audit (NELA)

Exclusion Criteria

Current participant exclusion criteria:
1. Planned epidural anaesthesia
2. Clinician refusal
3. Lack of mental capacity to consent to trial participation
4. Contraindications to RSC including allergy to local anaesthetic (LA), anatomical factors making RSC insertion impossible
5. Existing co-enrolment in another clinical study if:
5.1. The intervention in the other study is expected to influence the primary outcome (this will be considered by a senior clinician on a case-by-case basis)
5.2. It is considered too burdensome for the patient; or
5.3. It is not permitted by the other study
6. Previous enrolment in the CAMELOT trial

Previous participant exclusion criteria:
1. Clinician or patient refusal to participate
2. Planned epidural anaesthesia
3. Contraindications to Rectus Sheath Catheter (RSC) including allergy to local anaesthetic (LA)
4. Anatomical factors making RSC insertion impossible

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative pain control measured using the Overall Benefit of Analgesia Score (OBAS) over the first 5 postoperative days