The actions of apples on gut microbiota and bowel health in healthy adults

Not Applicable

Completed

• Conditions: Gut dysbiosis; Oral and Gastrointestinal - Normal oral and gastrointestinal development and function; Diet and Nutrition - Other diet and nutrition disorders

• Registration Number: ACTRN12621000540819
• Lead Sponsor: Plant and Food Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-05-07
• Study Completion: 2021-11-03
• Last Update Posted: 13 December 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Healthy adults between ages of 18-65 years inclusive with a BMI between 18-35 kg/m2.

Exclusion Criteria

Alarm features associated with bowel habit (recent changes in bowel habit (<3 months), rectal bleeding, weight loss, occult blood in stools, anaemia), anal fissures, bleeding haemorrhoids, and family history of Gastrointestinal (GI) cancer or Inflammatory Bowel Disease (IBD).

Chronic disease (cardiovascular, cancer, renal failure, previous gastrointestinal surgery (not including appendectomy or cholecystectomy), neurological conditions (e.g. multiple sclerosis, spinal cord injury, stroke).

Fasting blood glucose greater than 6.0 mmol/l

Women who are pregnant, breastfeeding or planning a pregnancy during the study period

Allergies to apple, alder or birch pollen and latex

Screening blood test results outside of the normal range which are deemed to be clinically significant

Study & Design

• Study Type: Interventional
• Study Design: Not specified