Comparison of two anesthestic gases on liver and kidney in hepatitis C patients
Completed
- Conditions
- Hepatitis CInfections and Infestations
- Registration Number
- ISRCTN10955668
- Lead Sponsor
- Theodor bilharz insitute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
1. Aged 20-60 years
2. Hepatitis C virus positive
3. Grade A patients (Child-Pugh classification of liver disease) with liver enzymes below double fold of normal reference range
4. Scheduled for laparoscopic cholecystectomy surgery
Exclusion Criteria
1. Grade B or C (Child-Pugh classification of liver disease) or with liver enzymes [alanine aminotransferase (ALT) or aspartate aminotransferase (AST) more than double fold of normal reference range
2. BMI over 30
3. Choronic renal disease and renalinsufficiency (creatinine>1,5 mg dl-1)
4. Use of alcohol or drugs
5. Diabetes Mellitus
6. Hypertenion
7. Unstable angina pectoris
8. History of myocardial infarction within the last 6 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Liver function is determined by measuring AST, ALT and alkaline phosphate in the blood postoperative, 1 day and 3 days postoperative<br>2. Kidney function is determined by measuring urea and creatinine in the blood postoperative, 1 day and 3 days postoperative
- Secondary Outcome Measures
Name Time Method Hepatitis C viral RNA is measured using blood testing preoperative and 3 days postoperative.