Toxicological Screening with LC-MS/MS in critically ill patients

Recruiting

• Conditions: F10-F19; Mental and behavioural disorders due to psychoactive substance use

• Registration Number: DRKS00024762
• Lead Sponsor: Allgemeine Intensivstation Universitätsklinik für Innere Medizin Medizinische Universität Graz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Suspected intoxication or coma of unknown etiology
- need for intensive care medicine
- adult

Exclusion Criteria

- anuria
- Missing substance detection in the LC-MS / MS in the urine

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Would the presence of the LC-MS / MS results in the urine have changed the initial clinical diagnosis?

Secondary Outcome Measures

Name	Time	Method
1. Would the existence of the exact substance identification have influenced the diagnostic and / or the treatment in the acute situation?<br><br>2. Can the severity of poisoning be determined on the basis of the semi-quantitative LC-MS / MS results in the serum?<br><br>3. Would the additional presence of the active substance concentration in the serum have influenced the diagnostic and / or the treatment in the acute situation?