Evaluation of Microbiology, Immunology and Gene expression in Pulp infections

Not Applicable

• Conditions: Periapical periodontitis; Diabetes mellitus type 2; C18.452.394.750.149; C07.320.830.700

• Registration Number: RBR-38dgqc
• Lead Sponsor: Programa de pós graduação em Odontologia do Instituto de Saúde de Nova Friburgo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-10-25
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Will be included older patients who wanted to participate in the research will be included; need for endodontic intervention or extraction for primary endodontic infection; presence of periapical injury

Exclusion Criteria

Patients who do not agree to sign the free and informed consent form; used antifungals, analgesics, anti-inflammatory drugs and antibiotics in the last 3 months, with endodontic lesions associated with periodontal disease, secondary endodontic infections, teeth with spontaneous pain, root fracture, pulp chamber exposure, impossibility of absolute isolation, curved channels, atresics. or calcified.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected that the individuals involved in the research will have their endodontic treatments performed and teeth extracted without recovery, ensuring the removal of foci of infection generating improvement in oral health, general and quality of life. The project will allow research to be developed in this line by the researchers involved, in addition to obtaining important data in the literature, which will be sent for publication in international scientific journals and congresses.

Secondary Outcome Measures

Name	Time	Method
It is hoped to promote a better understanding of the relationship between root canal microbiota and host response in triggering bone resorption, better understanding the complex system involving the development of endodontic infections to determine a more effective clinical protocol for treatment. improve the quality of life and minimize risks to the oral and general health of patients.