Clinical and microbiological evaluation after treatment at the site of chronic periodontal disease, with gels containing antimicrobial agents

Phase 2

• Conditions: Periodontal diseaseChronic periodontitis; C07.465.714.533.324

• Registration Number: RBR-226f6j
• Lead Sponsor: Faculdade De Odontologia de Ribeirão Preto

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-10
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with chronic periodontitis, with clinical insertion level equal to or greater than 6mm in two or more teeth and probing depth equal to or greater than 5mm in one or more periodontal sites (MACHTEI et al., 1992); Age range from 30 to 75 years old; Not having used antibiotics for at least 3 months; No history of allergy to the components present in the formulations to be tested (MDZ and Tetracyclines).

Exclusion Criteria

Severe cardiovascular disease; Pharmacokinetic problems such as nephropathy, liver disease, etc. Patients with a history of tetracycline allergy.

Study & Design

• Study Type: Intervention
• Study Design: Not specified