The Effect of Acute and Chronic L-Citrulline Extract Supplementation on Vasodilatory, Nitric Oxide Bioavailability and Exercise Performance in Human Adults
Not Applicable
- Conditions
- Healthy adults
- Registration Number
- JPRN-UMIN000036962
- Lead Sponsor
- Faculty of Sports Science and Recreation, Universiti Teknologi MARA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 18
Inclusion Criteria
Not provided
Exclusion Criteria
1. Smoker 2. Individual who consume any dietary supplements, quasi drugs or medicines within past 4 weeks. 3. On medication 4. Receiver of blood transfusion within 1 month prior to screening 5. Receiver of any investigational research agent prior to 30 days of experimental trial and individual who have a history of or current clinically significant disease. 6. Clinical population or an individual with heart/vascular related problem 7. Individual with the medical histories of alcoholism or drug dependence 8. Individual who have contraindication with high intensity exercise
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Resting blood pressure (systolic blood pressure, diastolic blood pressure and mean arterial pressure) 2. Continuous and intermittent endurance exercise performance
- Secondary Outcome Measures
Name Time Method 1. Nitric oxide level 2. Renal function (Urea nitrogen, Creatine) 3. Blood glucose and blood lactate 4. Plasma sodium and potassium 5. Oxygen cost of exercise 6. Oxidant and antioxidant markers 7. Cognitive function