HIV Prevention With Adolescents: Neurocognitive Deficits and Treatment Response

Not Applicable

Withdrawn

• Conditions: Risk Reduction Behavior; Sexual Behavior; Health Behavior; Drinking Behavior; Adolescent Behavior
• Interventions: Behavioral: INFORMATION-ONLY SEXUAL RISK REDUCTION; Behavioral: SEXUAL RISK REDUCTION + ALCOHOL RISK REDUCTION

• Registration Number: NCT01169922
• Lead Sponsor: University of New Mexico

Brief Summary

This research is examining how genetic and brain factors play a role in adolescents' health risk behavior as well as studying behaviors that young people engage in that may place them at risk for contracting a sexually transmitted disease like HIV/AIDS, and what kind of educational program works best to reduce these risky behaviors.

Detailed Description

A baseline assessment is conducted, including a computer questionnaire assessing personality characteristics, attitudes toward and experiences with sex, alcohol, drugs, and cigarettes, among other things. The participant also meets with a therapist to conduct a brief motivational interview at this time. A "Time-Line Follow-Back" is conducted; this notes incidences of sexual intercourse, alcohol use, marijuana use, and cigarette use in a 30-day period. An fMRI is conducted, and a saliva sample is gathered. During the second session of the study, participants are randomly assigned to either a sex and alcohol risk reduction intervention, or a sex risk reduction intervention. After the intervention, participants are contacted at 3 month intervals (3 months later, 6 months later, 9 months later, and 12 months later) to meet. At these "follow-up" meetings, another Time-Line Follow-Back is conducted, along with another computer questionnaire (again assessing attitudes toward and experiences with sex, alcohol, drugs, and cigarettes).

Study Timeline

• Study Start: 2007-10
• Primary Completion: 2007-10
• Study Completion: 2007-10
• Study First Submitted: 2010-07-23
• Study First Submitted QC: 2010-07-23
• Study First Posted: 2010-07-26
• Status Verified: 2024-01
• Last Update Submitted: 2024-01-08
• Last Update Posted: 2024-01-10

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Adolescents age 14-18
• Involved in Juvenile Justice System OR enrolled in a private school

Exclusion Criteria

• Currently taking anti-psychotics
• Involved in similar intervention-based study (2 similar studies being conducted simultaneously by this lab)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
INFORMATION-ONLY SEXUAL RISK REDUCTION	INFORMATION-ONLY SEXUAL RISK REDUCTION	Intervention contains information geared toward sexual risk reduction only.
SEXUAL PLUS ALCOHOL RISK REDUCTION	SEXUAL RISK REDUCTION + ALCOHOL RISK REDUCTION	Intervention contains information geared toward sexual risk reduction as well as alcohol risk reduction.

Primary Outcome Measures

Name	Time	Method
Time-Line Follow-Back (TLFB)	12-months post-intervention	A Time-Line Follow-Back is a review of a recent 30-day period of the participant's life, wherein they note which days they engaged in any of the following activities: sexual intercourse, alcohol use, marijuana use, cigarette use. Further details are also provided, such as whether a condom was used, how many alcoholic drinks were consumed, etc.

Secondary Outcome Measures

Name	Time	Method
Computer questionnaire	12 months post-intervention	Questionnaire completed by participant assesses sexual activity/consequences/attitudes, alcohol use/consequences/attitudes, marijuana use/consequences/attitudes, cigarette use/consequences/attitudes within past few months

Trial Locations

Locations (4)

Diversion Meetings (Youth Services Center); 🇺🇸 Albuquerque, New Mexico, United States

Youth Reporting Center (Youth Services Center); 🇺🇸 Albuquerque, New Mexico, United States

Albuquerque Academy; 🇺🇸 Albuquerque, New Mexico, United States

Sandia Preparatory School; 🇺🇸 Albuquerque, New Mexico, United States