Circadian rhythm in core body temperature and melatonin-levels in spinal cord injury

Completed

• Conditions: sleep disorder; Spinal cord injury; 10021112; 10041543

• Registration Number: NL-OMON34408
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Spinal cord injury
18-50 years of age

Exclusion Criteria

Obstructive disease of the gastro-intestinal tract, including diverticulitis and inflammatory bowel disease, or previous gastrointestinal surgery, except cholecystectomy and appendectomy.
Subjects that will undergo a MRI-scan within 2 days after one of the testing days, or subjects with a cardiac pacemaker or other implanted electromedical devices

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Melatonin and cortisol levels (using saliva-samples)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Core body temperature during 24 hrs (telemetry pill)<br /><br>Skin temperature (above and below the level of lesion)</p><br>