Efficacy of oranexidine gluconate in the prevention of catheter-related bloodstream infections
Phase 3
Recruiting
- Conditions
- Patients 18 years of age or older admitted to the ICU or HCU with a newly inserted central venous catheter or hemodialysis catheter
- Registration Number
- JPRN-UMIN000042343
- Lead Sponsor
- Jichi Medical University Saitama Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1980
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients with allergies to disinfectants 2) When the consent of the subject or his or her next of kin cannot be obtained 3) Patients with systemic skin diseases 4) The presence of a wound skin ulcer 5) When the catheter is replaced under the guidewire 6) Patients with antimicrobial catheters 7) Patients with antimicrobial-containing dressings 8) Patients participating in intervention trials related to CRBSI prevention (e.g., dressings, skin disinfectants, antimicrobial catheters, antimicrobial medications, etc.) 9) When it is judged to be difficult to obtain consent due to an emergency, etc.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of catheter-related infections
- Secondary Outcome Measures
Name Time Method 1) Incidence of catheter-related infections (per 1000 catheters/day) 2) In-hospital mortality rate 3) ICU mortality rate 4) Incidence of resistant bacteria (MRSA, Pseudomonas aeruginosa, VRE) 5) Adverse events (redness, urticaria, anaphylaxis, contact dermatitis etc.)