NCT00842478Unknown2 期
Effectiveness of Dental Brushing for Preventing Ventilator-Associated Pneumonia
Hospital Universitari Joan XXIII de Tarragona.2 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2005年5月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 400
- 试验地点
- 2
- 主要终点
- Ventilator-Associated Pneumonia (VAP)
研究概览
简要总结
Poor oral hygiene is associated with respiratory pathogen colonization and secondary lung infection.The possible association between oral care and incidence of VAP, and the role of dental plaque, mouth and tracheal colonization have not been firmly established. The investigators' hypothesis was that improving oral care with electrical toothbrushing might be effective in reducing the incidence of VAP.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult intubated patients
- •Without evidence of pulmonary infection (randomized within 12h of intubation if they were expected to remain ventilated for longer than 48 hours)
排除标准
- •Absence of dental pieces
- •Current diagnosis of pneumonia or massive bronchoaspiration
- •Tracheostomy (or expected within 48 hours)
- •Chlorhexidine allergy
结局指标
主要结局
Ventilator-Associated Pneumonia (VAP)
时间窗: 28 days
次要结局
未报告次要终点
研究者
研究点 (2)
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