Neuromuscular Electrical Stimulation in Patients With Interstitial Lung Disease
- Conditions
- Interstitial Lung Disease
- Registration Number
- NCT02497144
- Lead Sponsor
- Gazi University
- Brief Summary
Decreased exercise capacity and quality of life, increased dyspnea and fatigue perception and hypoxemia during exercise is seen in patients with interstitial lung disease. Impaired ventilatory response, increased lung compliance, ventilation-perfusion mismatching and inadequate peripheral circulation causes decreased exercise capacity. Another important factor that induce decreased exercise capacity is peripheral muscle weakness. In literature, there is no study investigated effects of neuromuscular electrical stimulation on functional exercise capacity, respiratory and peripheral muscle strength, pulmonary functions, physical activity level, dyspnea and fatigue perception in patients with interstitial lung disease.
- Detailed Description
In literature, there was increased quantity of study investigated effects of neuromuscular electrical stimulation in chronic lung disease patients. It was used as a pulmonary rehabilitation component especially in patients with decreased exercise capacity and peripheral muscle strength, intensely increased dyspnea inhibits exercise. It was demonstrated that neuromuscular electrical stimulation improved functional exercise capacity, peripheral muscle strength and quality of life.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- Diagnosed with interstitial lung disease
- Clinically stable
- Under standard medication
- Having no exacerbation or infection
- Cognitive disorders
- Orthopedic and neurological problems
- Contraindications to apply the neuromuscular electrical stimulation (pace maker, sensory defects, etc...)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Functional exercise capacity 6 weeks Six minute walk test
- Secondary Outcome Measures
Name Time Method Depression 6 weeks Montgomery Asberg Depression Rating Scale (MADRS) (Turkish versions of all scales)
Generic quality of life 6 weeks Short Form (SF-36) Health Survey
Disease specific quality of life 6 weeks Saint George Quality of Life Questionnaire
Inspiratory and expiratory muscle strength (MIP,MEP) 6 weeks Mouth pressure device
Dyspnea 6 weeks Modified Borg and Modified Medical Research Council (MMRC) Dyspnea scales
Peripheral muscle strength 6 weeks Hand held dynamometer
Fatigue 6 weeks Fatigue Severity Scale
Physical activity 6 weeks Metabolic holter
Cough related quality of life 6 weeks Leicester Cough Questionnaire
Maximal exercise capacity 6 weeks Incremental shuttle walk test
Pulmonary functions 6 weeks Spirometry
Trial Locations
- Locations (1)
Gazi University
🇹🇷Ankara, Turkey
Gazi University🇹🇷Ankara, Turkey