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Clinical Trials/NCT02714179
NCT02714179CompletedPhase 4

A Double Blind Randomised Controlled Trial of Preemptive and Preventive Use of Paracetamol for Pain Relief After Cesarean Section

Baskent University0 sites54 target enrollmentStarted: May 2015Last updated:
Conditions
Interventions
Drugs

Trial Snapshot

Phase
Phase 4
Status
Completed
Enrollment
54
Primary Endpoint
Visual analog score (VAS) for pain

Study Overview

Brief Summary

The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive versus preventive paracetamol on postoperative pain scores, patient satisfaction, total morphine consumption and the incidence of morphine-related side effects in patients undergoing cesarean section.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Masking
Triple (Care Provider, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to 40 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • 38 weeks pregnancy, elective cesarean section.

Exclusion Criteria

  • morbid obesity, cardiac failure, depression.

Arms & Interventions

Group Preemptive (Group PE),

Active Comparator

Group I: i.V. paracetamol 1 g (100 ml) was given 30 min before induction of anesthesia.

Intervention: Paracetamol was given intravenously in both group at different times (Drug)

Group Preventive (Group PV),

Active Comparator

Group II: i.V. paracetamol 1 g (100 ml) was given before the end of surgery.

Intervention: Paracetamol was given intravenously in both group at different times (Drug)

Outcomes

Primary Outcomes

Visual analog score (VAS) for pain

Time Frame: 24 hours

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ozlem Ozmete

Medical Doctor

Baskent University

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