A Double Blind Randomised Controlled Trial of Preemptive and Preventive Use of Paracetamol for Pain Relief After Cesarean Section
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Baskent University
- Enrollment
- 54
- Primary Endpoint
- Visual analog score (VAS) for pain
Study Overview
Brief Summary
The investigators designed a prospective randomized study to investigate the efficacy of intravenous (IV) preemptive versus preventive paracetamol on postoperative pain scores, patient satisfaction, total morphine consumption and the incidence of morphine-related side effects in patients undergoing cesarean section.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Masking
- Triple (Care Provider, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 40 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •38 weeks pregnancy, elective cesarean section.
Exclusion Criteria
- •morbid obesity, cardiac failure, depression.
Arms & Interventions
Group Preemptive (Group PE),
Group I: i.V. paracetamol 1 g (100 ml) was given 30 min before induction of anesthesia.
Intervention: Paracetamol was given intravenously in both group at different times (Drug)
Group Preventive (Group PV),
Group II: i.V. paracetamol 1 g (100 ml) was given before the end of surgery.
Intervention: Paracetamol was given intravenously in both group at different times (Drug)
Outcomes
Primary Outcomes
Visual analog score (VAS) for pain
Time Frame: 24 hours
Secondary Outcomes
No secondary outcomes reported
Investigators
Ozlem Ozmete
Medical Doctor
Baskent University