A randomised study of continuous infusional 5-Fluorouracil (5FU) with or without bolus mitomycin-C in patients with carcinoma of unknown primary origi
Completed
- Conditions
- Carcinoma of unknown primary originCancerMalignant neoplasm without specification of site
- Registration Number
- ISRCTN63374575
- Lead Sponsor
- The Royal Marsden NHS Foundation Trust (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 88
Inclusion Criteria
1. Histological evidence of carcinoma of unknown primary site
2. Patients evaluable for response
3. Must have bi-dimensionally measurable disease as assessed by chest X-ray or Computed Tomography (CT) scan
4. Disease must be outside previously irradiated areas
Exclusion Criteria
Not provided at time of registration
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Added 05/08/09:<br>1. tumour response<br>2. survival<br>3. toxicity<br>4. quality of life (QoL)
- Secondary Outcome Measures
Name Time Method ot provided at time of registration