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A Randomised Study of continuous infusion 5-Fluorouracil (5FU) with or without bolus Mitomycin-C in Patients with Advanced Pancreatic Cancer

Completed
Conditions
Pancreatic cancer
Cancer
Malignant neoplasm of pancreas
Registration Number
ISRCTN61961630
Lead Sponsor
The Royal Marsden NHS Foundation Trust (UK)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
208
Inclusion Criteria

Histological evidence of locally advanced or metastatic carcinoma of the pancreas not amenable to surgery or radiotherapy. Alternatively patients would have radiologically measurable evidence of locally advanced or metastatic carcinoma of the pancreas not amenable to surgery or radiotherapy, without histological evidence but with a carcinoembryonic antigen (CEA) above 50.

Exclusion Criteria

Does not match inclusion criteria

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Added 05/08/09:<br>1. tumour response<br>2. survival<br>3. toxicity<br>4. quality of life (QoL)
Secondary Outcome Measures
NameTimeMethod
ot provided at time of registration
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