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Clinical Trials/NCT05100368
NCT05100368
Completed
Not Applicable

The Prognostic Value of Serum Biomarkers in Ewing's Sarcoma

Istituto Ortopedico Rizzoli1 site in 1 country1,000 target enrollmentApril 2, 2021
ConditionsSarcoma, Ewing

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sarcoma, Ewing
Sponsor
Istituto Ortopedico Rizzoli
Enrollment
1000
Locations
1
Primary Endpoint
5-year survival
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Extraction of laboratory data from blood tests prior to surgical and chemotherapy and other histological, clinical and instrumental data related to the patient's history from the digitized medical Digitized medical records and analysis of the same. The medical records of 1000 patients from January 1, 2000, until December 31, 2020

Registry
clinicaltrials.gov
Start Date
April 2, 2021
End Date
July 1, 2021
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Costantino Errani

Principal Investigator

Istituto Ortopedico Rizzoli

Eligibility Criteria

Inclusion Criteria

  • Patients with Ewing's Sarcoma and osteosarcoma with established diagnosis;
  • Patients with age ≥ 2 years;
  • Minimum follow-up duration of 2 years;
  • Medical records, complete blood work and instrumental examinations; Regular follow-up.

Exclusion Criteria

  • Patients with Ewing's sarcoma or osteosarcoma who have received medical treatment (surgery radiotherapy or chemotherapy) in other institutions prior to admission to the Rizzoli Orthopaedic Institute.

Outcomes

Primary Outcomes

5-year survival

Time Frame: at baseline (Day0)

Evaluation of 5-year survival in relation to histologic, laboratory, clinical, and instrumental laboratory, clinical and instrumental factors

Secondary Outcomes

  • Rate of local recurrence(at baseline (Day0))

Study Sites (1)

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