Comparison between two low doses of Amitriptyline in the management of chronic neck pain. A Randomized double-blind comparative study.

Not Applicable

• Conditions: Nervous System Diseases; Musculoskeletal Diseases; Orthopaedics

• Registration Number: PACTR202003721200086
• Lead Sponsor: Fayoum University Hospitals

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-12-03
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Other
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

1.Presence of CNP for more than 15 days/month during at least three consecutive months.
2. Patients without previous trauma.
3. Patients free from other neurologic disorders except for chronic tension headaches.
4. Age from18 to 75 years.
5. Normal neurologic examination (performed by a neurologist) except for pericranial tenderness.
6. No imaging abnormalities except for a loss of cervical lordosis.

Exclusion Criteria

1.The presence of neurologic disorder revealed an abnormal clinical examination.
2. Abnormal imaging or history of cervical disc disease.
3. Migraine headache.
4. History of trauma.
5. Major depressive disorder.
6.Analgesic abuse.
7. History of intolerance to tricyclic or tetracyclic antidepressants.
8. Current psychiatric disorder.
9. Glaucoma, cardiac rhythm abnormalities, severe constipation.
10. Patients on medications for CNP other than NSAID or paracetamol taken during the last month.
11. Pregnancy in women and prostatic symptoms in men.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
eck Pain Disability Index. NPDI

Secondary Outcome Measures

Name	Time	Method
eck pain intensity;Athens Insomnia Scale;Anxiety and depressive symptoms will be evaluated with Hospital Anxiety and Depression Scale (HADS),