Comparison of fluid administration guided by ultrasound of neck vessels versus routine fluid administration for prevention of low blood pressure following spinal anaesthesia in pregnant patient for caesarean section.
- Conditions
- Pregnancy, childbirth and the puerperium,
- Registration Number
- CTRI/2023/07/055498
- Lead Sponsor
- Maulana Azad Medical College and Lok Nayak Hospital.
- Brief Summary
Spinal anaesthesia is the anaesthetic techniqueof choice for caesarean section. The most common side effect of spinal anaesthesia is hypotension and has a very high incidence rate.It is caused by spinal block induced sympatholysis which leads to vasodilation and thereby hypotension. The administration of intravenous fluids to optimise the blood volume during sympathectomy has been widely used as first line therapy. Ultrasound has been used to estimate the pre-operative intravascular volume status. Internal jugular vein is an easily accessible vessel for assessment of intravascular fluid volume .Thus, we plan to undertake this study to evaluate and compare internal jugular vein collapsibility index guided versus conventional crystalloid administration on post spinal hypotension in pregnant patients undergoing caesarean section.
The study will be conducted in the Department of Anaesthesiology, Maulana Azad Medical College and associated Lok Nayak Hospital, New Delhi. In this study, pregnant patients aged between 18- 40 years scheduled for elective caesarean section will be recruited.
Primary objective of the study is to evaluate the incidence of post spinal hypotension whereas secondary objective is to evaluate the amount of crystalloid administered before spinal block, to evaluate the number of episodes of hypotension, vasopressor requirement, and total amount of fluid administered till cord clamping and to evaluate the APGAR score of the baby at 1 minute and 5 minutes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 70
- Patients of American Society of Anesthesiologists(ASA) Physical status 2.
- Term, singleton pregnancy 3.
- Height of the patient ( 150- 170) cms.
- Absolute contraindications for spinal anaesthesia -localized sepsis,deranged coagulation profile,severe hypovolemia, severe aortic stenosis, severe mitral stenosis.
- Relative contraindications for spinal anaesthesia- pre existing neurological deficits, severe spinal deformity.
- Significant hepatic, renal or cardiovascular disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the incidence of post spinal hypotension BP measurement will be done every 2 minutes for the first 15 minutes after spinal anaesthesia followed by every 5 minutes till the end of surgery to assess hypotension
- Secondary Outcome Measures
Name Time Method 1. Amount of crystalloid administered before spinal block. 2.Number of episodes of hypotension
Trial Locations
- Locations (1)
Maulana Azad Medical College and Lok Nayak Hospital
🇮🇳Central, DELHI, India
Maulana Azad Medical College and Lok Nayak Hospital🇮🇳Central, DELHI, IndiaDr Anurag SinghPrincipal investigator7987201149as899270@gmail.com