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临床试验/NCT07255989
NCT07255989已完成不适用

A Study About the Role of Gut Microbiome in Fatty Liver -Fatty Pancreas and Heart Diseases .

Benha University2 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2023年4月19日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
50
试验地点
2
主要终点
prevelance of fatty pancreas 60% which is more common than the expection

研究概览

简要总结

Example 2: Interventional study The goal of this observational study is to learn know about the use of FibroScan in diagnosis of fatty pancreas in obese and non obese patients which done for the first time at worldwide as well as Egypt .The participtants already came to do liver FibroScan at center of excellence , Benha University , Egypt. Untill now the diagnosis of fatty pancreas by MRI which accurate and specific and diagnose fatty pancreasif it is more than 6.2% . lough the use of abdominal ultrasound also is proved . The use of digital fibroscan which is easy non invasive , unique as well as we can diagnose fibrosis too in the same sitting .So it is highly recommended to be add with examination of liver by fibroscan.

详细描述

This Interventional study done for subjects attend Center of excellence , at Benha University . aged of patients was from 30 years to 70 years old , both male and females , obese or non and DM or non . the patients came to do fibroscan to liver . Lab investigations in the form of CBC ,ESR , liver function tests , kidney function tests. Complete lipid profile , HbA1c .clincal and physical examinations done as regard BMI, past history for metabolic diseases , operations and blood transfusion. FibroScan done first to liver while the patients fastinf at least 3 hours with the know specific position recommendation (banana like ).The position for pancreas examination by fibroScan differe as the patient dorsal position/ recumbancy and his hand behind his head . take deep breah and slighlty keep it . some tilting to the left or right . the probe of fibroscan in the epigastrium under the left rib.which totally differe than liver which in the RT anterior axillary line 8 th intercostal space.picture taken , the unique , novality of this modility is the diagnosis of fibrosis too like liver.Grading of aftty pancreas was done as well as fibrosis of pancreas as follow :S1 =264 dB/m , S2 =276 dB/m and S3 =336 dB/m .

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

盲法说明

As we are care to early diagnosis of fatty pancreas by simple non invasive method

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • - Subjects aged from 30 to 70 years old , both male and females , DM or not obese or non obese

排除标准

  • Exclusion Criteria:
  • Subjects with significant amount of alcohol consumption or history of alcohol consumption (>60 g/day).
  • History of steatogenic medications (amiodarone, valproic acid, corticosteroids, tetracyclines).
  • Patients with a previous history of pancreatic disease

结局指标

主要结局

prevelance of fatty pancreas 60% which is more common than the expection

时间窗: 6 months

the need to raise uo the importance to use FibroScan to diagnosis of fatty pancreas which is novel , unique and invasive , specific

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Prof.Reda Mohamed Elbadawy

professor Hepatology , Gastroenterology

Benha University

研究点 (2)

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