Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury
- Conditions
- Mechanically Ventilated ICU Patients
- Registration Number
- NCT01541514
- Lead Sponsor
- University of Chicago
- Brief Summary
The overall purpose to the study is to prospectively study how often patients with and without acute lung injury (ALI) have patient-ventilator asynchrony demonstrated as stacked breaths. The investigators seek to describe the quantity of stacked breaths by continuously recording flow, volume, and pressure waveforms routinely displayed on the vent. The investigators also seek to describe how primary ICU teams manage asynchrony documenting interventions of sedation or vent manipulation and what modality is most successful.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
age > 18 years intubated and mechanically ventilated diagnosed with acute lung injury (ALI) or requiring mechanical ventilation for reasons other than ALI
neurological deficits (acute or chronic) that prevent effective diaphragm activity.
- Neuromuscular disease affecting the diaphragm
- Neuromuscular blockade
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method double stacks number per minute over 5 minutes ventilator waveform recording
- Secondary Outcome Measures
Name Time Method mode of ventilation 30min ventilator adjustment
level of sedation baseline Richmond Agitation Sedation Score
Trial Locations
- Locations (1)
University of Chicago Medical Center
🇺🇸Chicago, Illinois, United States