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Clinical Trials/NCT01541514
NCT01541514CompletedNot Applicable

Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury

University of Chicago1 site in 1 country30 target enrollmentStarted: July 2011Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
30
Locations
1
Primary Endpoint
double stacks
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The overall purpose to the study is to prospectively study how often patients with and without acute lung injury (ALI) have patient-ventilator asynchrony demonstrated as stacked breaths. The investigators seek to describe the quantity of stacked breaths by continuously recording flow, volume, and pressure waveforms routinely displayed on the vent. The investigators also seek to describe how primary ICU teams manage asynchrony documenting interventions of sedation or vent manipulation and what modality is most successful.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •age > 18 years intubated and mechanically ventilated diagnosed with acute lung injury (ALI) or requiring mechanical ventilation for reasons other than ALI

Exclusion Criteria

  • •neurological deficits (acute or chronic) that prevent effective diaphragm activity.
  • •Neuromuscular disease affecting the diaphragm
  • •Neuromuscular blockade

Outcomes

Primary Outcomes

double stacks

Time Frame: number per minute over 5 minutes

ventilator waveform recording

Secondary Outcomes

  • mode of ventilation(30min)
  • level of sedation(baseline)

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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