Detecting the change of acupuncture points in patients with chronic low back pai

Not Applicable

Completed

• Conditions: chronic low back pain; Alternative and Complementary Medicine - Other alternative and complementary medicine; Musculoskeletal - Other muscular and skeletal disorders; Neurological - Other neurological disorders

• Registration Number: ACTRN12619000614190
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-04-24
• Study Completion: 2019-12-13
• Last Update Posted: 13 December 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

A change has been made on criteria for healthy controls:
We change No history of back pain or back related health issue to Don't have back pain or back related health issue in the previous 12 months

The complete content in update field should be:
1. Patients with chronic low back pain
-Meet the diagnostic criteria of low back pain in NICE clinical guideline (No.59);
-not less than 18 years old;
-Pain duration more than 3 months (either intermittent or consecutive pain);
-Signed informed consent.

2. Healthy controls
-Healthy controls will be matched to patients with low back pain in terms of sex, ethnicity, and age within the range of 5 years;
-Good general health;
-Don't have back pain or back related health issue in the previous 12 months;
-Signed informed consent.

Exclusion Criteria

1. Patients with chronic low back pain
-Serious spinal disorders including malignancy, vertebral fracture, spinal infection, spinal stenosis, inflammatory spondylitis, cauda equine syndrome;
-History of spinal surgery;
-Take medications like acetaminophen, duloxetine, benzodiazepines, opioids, corticosteroids, anticonvulsants, NSAIDs in the prior 1 week;
-Received acupuncture for low back pain in the latest 4 weeks;
-Accompanying serious respiratory, circulatory, endocrine, urinary, or digestive system disease, etc;
-Mental ill health, such as dementia, schizophrenia, addictive behaviors; or severe depression (PHQ-9 score more than or equal to 15), severe anxiety (PASS score more than 38).
-Unable to communicate in English;
-Severe disability (RDQ more than or equal to 20), flu, fibromyalgia, rheumatoid arthritis, sacroiliac joint pain or injury.
-Are pregnancy or lactation period;
-Have skin damage or open wound on the lower back;

2. Healthy controls
-As the points of interest are all on bladder meridian, health problems related to bladder meridian will be excluded;
-BL 23 and BL 25 are the Back-shu points of kidney and large intestine respectively, so the diseases related to these 2 organs will be excluded;
-Taking medications like acetaminophen, duloxetine, benzodiazepines, opioids, corticosteroids, anticonvulsants, NSAIDs in the prior 1 week for any reasons;
-Mental ill health, such as dementia, schizophrenia, addictive behaviors; or severe depression (PHQ-9 score more than or equal to 15), severe anxiety (PASS score more than 38).
-Unable to communicate in English;
-Pregnancy or lactation period;
-Skin damage or wound on points;

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome is pressure pain threshold (PPT), PPT is defined as the minimal intensity of stimulus to induce initial pain that can be perceived by a person. <br>AlgoMed (Medoc Ltd., Ramat Yishai, Israel) will be used to quantitatively detect the pressure pain threshold (PPT) on low back pain related acupoints (Bilateral BL 23, BL 25, BL40) and 2 points that are 2cm lateral to BL 25.[immediate assessment]