The effect of Hydrocortisone,Vitamin C and Thiamine in treatment of patients with severe Sepsis/Septic shock

Phase 2

Recruiting

• Conditions: septic shock,severe sepsis.; Severe sepsis with septic shock; R65.21

• Registration Number: IRCT20220219054058N1
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 8 March 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

NO covid 19 Disease(PCR negative)
Age 18or higher
No pregnancy
No G6PD deficiency
No initial diagnosis of: Stroke, Acute Coronary syndrome, Active Gastrointestinal bleeding, Burns and Trauma
No use of vasopressors more than 24 hours before entering the study

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality rate, Duration of intubation, Duration of stay in the intensive care unit, Duration of vasopressor, CRP, Lactate, Severity of illness. Timepoint: Mortality at the end of 7 days, Intubation period up to 7 days, Mean daily disease intensity up to 3 days, Mean CRP level on the first, third and fifth day, Duration of stay in intensive care unit up to 7 days, Duration of hospital stay, Mean level Lactate on the first, third and fifth day, Duration of receiving vasopressor up to 7 days. Method of measurement: Questionnaire filled out by Intern.