Comparison of intravenous dexmedetomidine and clonidine effect in Trans-ABdominal Hysterectomy undergoing in spinal anaesthesia given by bupivacaine

Not yet recruiting

• Conditions: Multigravida

• Registration Number: CTRI/2018/07/014690
• Lead Sponsor: RNT Medical College

Brief Summary

This is a Randomized, prospective double blind placebo control study to evaluate the effect of intravenous Dexmedetomidine and clonidine on the characteristics of subarachnoid block by Bupivacaine in Trans-Abdominal Hysterectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-07
• Last Update Posted: 2018-06-28

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 150

Inclusion Criteria

ASA grade I and grade II.

Exclusion Criteria

ASA grade III or above BMI > 30kg/m2 Who will refuse to give consent for spinal anaesthesia History of cardiac rhythm like bradycardia or A-V junction bkock History of preoperative intake of ACE inhibitors, calcium channel blockers, beta blockers, alpha 2 adrenergic receptor antagonist.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To Evaluate of the effect of Intravenous Dexmedetomidine and Clonidine on the characteristics of Subarachnoid block by Bupivacaine in Trans-Abdominal Hysterectomy	1min, 2mins, 5mins, 10mins, 15mins, 30mins, 45mins, till end of surgery

Secondary Outcome Measures

Name	Time	Method
To determine the hemodynamic consquence of IV Dexmedetomidine and Clonidine administration	1min, 2mins, 5mins, 10mins, 15mins, 30mins, 45mins, till end of surgery

Trial Locations

Locations (1)

Obestetrics & Gynaecology Operation Theatre; 🇮🇳 Udaipur, RAJASTHAN, India

Obestetrics & Gynaecology Operation Theatre

🇮🇳Udaipur, RAJASTHAN, India

Dr Vikram Bedi

Principal investigator

9829025373

vbedimd@gmail.com