Effect of intravenous hydrocortisone in patients with septic shock
Not Applicable
- Conditions
- Septic shock.Septic shock
- Registration Number
- IRCT2014080211956N2
- Lead Sponsor
- Mashhad University of medical Siences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 160
Inclusion Criteria
All patients above eighteen who admitted in Imam Reza Hospital of Mashad with diagnosis of septic shock and do not respond to vasopressor therapy more than 60 minutes are included.
Those who suffer from adrenal insufficiency before admission or had tuberculosis or had been treated with ketoconazole or estrogens are excluded. Those with no consent with the plan are also excluded
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mortality in 28 days. Timepoint: During 28 days. Method of measurement: Death records.
- Secondary Outcome Measures
Name Time Method Response to vasopressor. Timepoint: The time that there is no need to vasopressor. Method of measurement: Normal central vein pressure (6-12 Cm H2O), mean arterial pressure more than 65 mmHg.