Heredity of Retinal Vessel Tortuosity
Completed
- Conditions
- Retinopathy of Prematurity
- Registration Number
- NCT00427063
- Lead Sponsor
- Glostrup University Hospital, Copenhagen
- Brief Summary
The purpose of this study is to asses the relative influence of genetic and environmental influence on the tortuosity of retinal arterioles in eyes of 218 healthy Danish twins aged 20-46 years. We expect to find a high heredity for the variation in tortuosity. This knowledge can contribute to the elucidation of the pathology in retinal diseases.
- Detailed Description
All persons underwent an ophthalmic examination including refraction, slit lamp biomicroscopy and digital fundus photography. Two independent graders (both with an MD degree) made a visual grading of the severity of tortuosity of the retinal arterioles in the fundus images.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 218
Inclusion Criteria
- Samesex twin pairs of self-assessed good health
Exclusion Criteria
- Diabetes mellitus
- Hypertension
- Thyroid disease
- Cataract or other opacities of the refractive media
- Missing fundus photographs
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Ophthalmology Glostrup Hospital
🇩🇰Glostrup, Copenhagen County, Denmark
Department of Ophthalmology Glostrup Hospital🇩🇰Glostrup, Copenhagen County, Denmark