Epidemiologic, Laboratory, and Clinical Characterization of Individuals With Ocular Diseases

Nanjing Medical University1 site in 1 country800 target enrollmentOctober 2004

ConditionsOcular Diseases

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Ocular Diseases
Sponsor: Nanjing Medical University
Enrollment: 800
Locations: 1
Last Updated: 17 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Environmental and genetic factors may play a role in the progression of ocular diseases (cataract, retinopathy, age-related macular degeneration, glaucoma, retinal detachment, ocular tumor, etc.). The goal of this project is to establish a series of case-control studies to evaluate risk factors of ocular diseases in China.

Detailed Description

This study is designed to investigate the epidemiologic, genetic, laboratory and clinical characterization of individuals with ocular diseases (cataract, retinopathy, age-related macular degeneration, glaucoma, retinal detachment, ocular tumor, etc.). We will accrue approximately 800 patients as experimental group. The control group consists of age/sex frequency-matched subjects who will be confirmed without ocular diseases. We will explore the environmental (including family history, life style, diet, physical activity, neuropsychological functioning，plasma levels of oxidative stress and angiogenic factors, etc.) and genetic (including oxidative stress and angiogenic factors, etc.) risk factors. We will study the association between various environmental risk factors with the clinical characterization and correlation between the genetic polymorphisms and the presence of various ocular diseases.

Registry

clinicaltrials.gov

Start Date

October 2004

End Date

TBD

Last Updated

17 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Nanjing Medical University

Eligibility Criteria

Inclusion Criteria

•This is a study only of Chinese.
•Subjects will be allowed to participate if they self-identify as Chinese.
•Individuals with ocular diseases (cataract, retinopathy, age-related macular degeneration, glaucoma, retinal detachment, ocular tumor, etc.) will be allowed to participate. To participate in the study as the control, subjects should be confirmed without ocular diseases.