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Prospective randomised controlled trial of video assisted thorascopic (VATS) cytoreductive pleurectomy compared to talc pleurodesis in patients with suspected or proven malignant mesothelioma - MesoVATS study

Conditions
Mesothelioma
Registration Number
EUCTR2011-001121-24-GB
Lead Sponsor
Papworth Hospital NHS Trust
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Confirmed or suspected mesothelioma (any sub-type) 2. Associated pleural effusion present 3. Clinically fit and suitable for VAT cytoreductive pleurectomy 4. Able to give Informed consent
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

1. Unfit for VAT pleurectomy 2. Absence of a pleural effusion 3. Previous attempted pleurodesis by any approach 4. Previous malignancy (Patients who have had a previous malignancy for which they are no longer receiving treatment are eligible to take part in the study provided that they have a confirmed diagnosis of mesothelioma. Those who have had a previous malignancy and do not have a confirmed diagnosis of mesothelioma will not be eligible to take part as we cannot be certain that the pleural disease/effusion is not related to the original cancer). 5. Age < 18

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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