Comparison of the Effects of Anesthetic Techniques Used for Cesarean Delivery on Neonatal Cerebral and Renal Oxygenation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 主要终点
- Change in renal and cerebral regional oxygenation (rSO2) in newborn
研究概览
简要总结
Neonatal adaptation to extrauterine life has many physiological changes in neonatal organ systems. These adaptative changes may be affected such as type of delivery and anesthesia management at birth. near infrared spectroscopy (NIRS) is a popular non-invasive method that can be used in newborns thus monitorize tissue oxygenation regularly. In this study we have purposed to compare the effects of general anesthesia versus spinal anesthesia on newborn's cerebral and renal oxygenation in elective cesarean operations
详细描述
The cases divided into two groups those spinal anesthesia group ( group:1; n:30 ) and general anesthesia group (group:2; n:30). The preoperative and intraoperative mean arterial pressures (MAP), heart rate (HR), arterial oxyhemoglobin saturation (SpO2), intraoperative blood loss values of pregnants and 1st-5th minute APGAR scores, preductal and postductal SpO2, perfusion index, heart rates, body temperature, cerebral and renal regional oxygen saturations of newborns after birth have been recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who undergo elective cesarean
- •American Society of Anesthesiologists class 1 to 2
- •Ability to consent
- •Gestational age: from 37 to 41 weeks
排除标准
- •Pulmonary disease
- •History of allergic reaction to local anaesthetics
- •Peripheral neuropathy
- •Neurologic disease
- •Coagulation disorders
- •newborns with anomalies
- •low birth weight newborns
- •newborns needing neonatal resuscitation
结局指标
主要结局
Change in renal and cerebral regional oxygenation (rSO2) in newborn
时间窗: 60 minutes after birth
Assessed at third and fifth minutes and then every 5 minutes after birth
次要结局
- body temperature(60 minutes after birth)
- perfusion index(60 minutes after birth)
- preductal SpO2(60 minutes after birth)
- postductal SpO2(60 minutes after birth)
- apgar scores(1st and 5th minute after birth)