Effectiveness of Ozone Therapy Treatment of Endometriosis

Not Applicable

Recruiting

• Conditions: Endometriosis; C12.100.250

• Registration Number: RBR-10fhfdt4
• Lead Sponsor: niversidade Brasil

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-07-06
• Last Update Posted: 26 July 2023
• Study Completion: 2024-04-02

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women with Endometriosis with laboratory diagnosis; age group between 20 and 50 years; ability to respond to questionnaires; ability to consent to participation in the study and sign informed consent

Exclusion Criteria

Volunteers with a history of hysterectomy or oophorectomy; pregnant or breastfeeding women; BMI greater than 30kg/m2 have a history of previous physical abdominal trauma in the last 3 months; use of psychotropic medications; infectious diseases (tuberculosis, leprosy, HIV, systemic fungal diseases) or any other similar condition; severe underlying disease (heart, kidney, liver, lung) or malignancy; diabetes mellitus and decompensated hyperthyroidism; history of topical and aesthetic treatments in the last 3 months; glucose 6-phosphate deficiency; lack of ability or willingness to provide informed consent; lack of availability for visits or to comply with study procedures; hypersensitivity to ozone therapy treatment, climacteric or premature ovarian failure; pelvic pain complaints; use of oral or injectable hormonal contraceptives; progestogens

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluate pain during the 10 weeks of treatment and for 60 days after the applications, verified by the Visual Analog Scale screening. This performance is expected to assess whether there has been a reduction in pain based on the verification of a variation of at least 2 points in pre- and post-intervention follow-ups

Secondary Outcome Measures

Name	Time	Method
Evaluate sexual function and quality of life during the 10 weeks of treatment and for 60 days after the applications, verified by the Endometriosis Health Profile Questionnaire (EHP-30). It is expected to evaluate the improvement or not of the patient's sexual function and quality of life from the verification of a variation of at least 2 points of pre- and post-intervention measurements.;Evaluate the anxiety and the level of depression during the 10 weeks of treatment and for 60 days after the applications, verified by the Beck Hopelessness Scale and sessions of dealing with”, overcoming”, coping”, taking care of”, endure” (short COPE). It is expected to evaluate the level of anxiety and the level of depression from the verification of a variation of at least 2 points of exercises pre and post-intervention.