Investigating the influence of methylphenidate on perceptual decisions in healthy, young adults

Phase 4

Recruiting

• Conditions: Symptoms of inattention; Symptoms of hyperactivity; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12619001752156
• Lead Sponsor: Monash University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-12-10
• Last Update Posted: 17 August 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

All four grandparents Caucasian - to ensure consistency in drug absorption rates
Right handed - to reduce noise associated with differences in organisation of brain function
Females taking combined oral contraceptive pill - to control for any differing absorption rates that may be the result of fluctuating hormones

Exclusion Criteria

- Pregnant or breastfeeding - to prevent any potential risk of harm methylphenidate may cause for unborn or newborn children
- History of psychiatric or neurological illness (including head injuries) - such conditions may confound results
- Use of psychotropic medication or significant drug use - could confound results, as any possible alteration in brain function from previous drug use may interfere with substances administered in this study
- Current smokers - May influence sensitivity of nicotine receptors
- Alcohol dependence (more than 24 units/week) - may influence dopamine receptor availability or sensitivity
- Individuals with contraindications to methylphenidate

Study & Design

• Study Type: Interventional
• Study Design: Not specified