The Effect of Diet on the Renal Function of Renal Transplant Patients: Nutritional Status and Quality of Life

Not Applicable

• Conditions: Kidney Transplantation; Renal Insufficiency, Chronic; Diabetes Mellitus; Sarcopenia; Dyslipidemias; Obesity; Proteinuria.; C12.777.419.780.750; E02.870.500; C18.452.394.750

• Registration Number: RBR-8xbqk5
• Lead Sponsor: niversidade Federal do Rio Grande do Norte

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-06-21
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Individual volunteers, submitted to Kidney Transplantation at University Hospital Onofre Lopes (HUOL), of both genders, aged 18 years or over.

Exclusion Criteria

Individuals with a baseline diagnosis of Segmental and Focal Glomerulonephritis (GESF); performing multiple organ transplantation; history of recurrent transplantation due to chronic rejection; illiterate individuals who do not have a literate companion; individuals who did not complete all the steps foreseen in the study.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Expected outcome 1: Difference in proteinuria values, verified by the Albumin-Creatinine Ratio (RAC) at 6 months, from the observation of maintenance of adequate values ??or a reduction of at least 25% in the intervention group.;Expected outcome 1: Difference in proteinuria values, verified by the Albumin-Creatinine Ratio (ACR) at 12 months, after a reduction of at least 25% in the intervention group.

Secondary Outcome Measures

Name	Time	Method
Expected outcome 1: Reduction of body fat percentage and increase of lean mass, verified by the X-ray dual absorptiometry (DXA) method, in the intervention group.;Expected outcome 2: Control of body weight, allowing gain of up to 5% of initial body weight in the intervention group.;Expected outcome 3: Improvement of the quality of life, verified by the significant increase in SF-36 score in the intervention group.;Expected outcome 4: Significant improvement in lipid profile, with reduction of triglycerides, total cholesterol and LDL-c levels in the intervention group.;Expected outcome 5: Significant improvement in the glycogen profile, with reduction of fasting glycemia levels and glycated hemoglobin, in the intervention group.