MedPath

Drug Wastage : Observational Study in the Operating Rooms of France

Completed
Conditions
Drug Use
Interventions
Other: Quantification of injectable drugs wastage
Registration Number
NCT05609864
Lead Sponsor
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Brief Summary

Environmental awareness is leading medical field to question its responsibility and possibilities for action.

Drug residues can have a major environmental impact as per their bioaccumulation, toxicity and persistence characteristics, depending on where they are discarded. In France, drug residues should be disposed of by incineration, but in practice this is not systematic. Moreover, data on drug wastage in the operating rooms by anesthesia department are rare.

The GAME-OvBLOC observational study aim to evaluate drug wastage in the operating rooms by anesthesia department in France and to propose ways of improving health care practices.

Detailed Description

Observational study with data collection over a 24-hour business day. Data collected refer to healthcare team's practices and patients.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
3763
Inclusion Criteria
  • All patients who will need an anesthesia act in operating room during a 24 hours period
Exclusion Criteria
  • Patient opposition to participate in the study or parents opposition if the patient is a child or patient family opposition if the patient is not capable of being informed

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Injectable drugsQuantification of injectable drugs wastagePatient's data and data relating to prepared/administrated/discarded injectable drugs will be collected during 24 hours in the operating rooms by anesthesia department
Primary Outcome Measures
NameTimeMethod
Ratio of overall wastage in milliliter (mL) of prepared and discarded injectable drugs, to overall volume in milliliter (mL) of prepared injectable drugs24 hours

Wastage is defined as : any prepared and unused drug that remains in syringe

Secondary Outcome Measures
NameTimeMethod
Cost of overall injectable drugs wastage24 hours

Estimated cost of drug residues will be evaluated for each drug by the following formula :

volume of discarded injectable drugs x theoretical price

Use of alternative to injectable drugs24 hours

Alternatives : local anaesthesia and anaesthetic gases

Reason for discarding drug residues24 hours

The reason of waste full syringe will be noticed : 1/ prepared in advance and not used ; 2/ prescription change ; 3/ preparation error ; 4/ other reason

Describe drug wastage for each kind of surgery/anesthesia24 hours

Drug wastage according to type of surgery and anaesthesia

Drug residues discarding process24 hours

Questionnaire on nursing practices on the choice of waste disposal circuits according to drugs

Describe drug wastage for each age group24 hours

Drug wastage according to the following age groups : adult (≥18 years old) and pediatrics (\< 1 year old, 1-5 years old, ≥ 6 years old)

Describe waste and environmental impact of used plastic syringes24 hours

Number and volume of used syringes, use of pre-filled syringes, refilling of syringes and multi-patient use.

Environmental impact is indirectly assessed by type of plastic used and the transport distance from the production site to France.

Trial Locations

Locations (83)

Centre Hospitalier de Charleville-Mézières

🇫🇷

Charleville-Mézières, Ardennes, France

Hôpital La Timone (AP-HM)

🇫🇷

Marseille, Bouches-du-Rhône, France

Centre Hospitalier Henri Mondor

🇫🇷

Aurillac, Cantal, France

CHU de Dijon

🇫🇷

Dijon, Côte d'Or, France

CHRU de Brest

🇫🇷

Brest, Finistère, France

Centre hospitalier Sud Francilien

🇫🇷

Corbeil-Essonnes, Essonne, France

Centre Hospitalier d'Arcachon

🇫🇷

La Teste-de-Buch, Gironde, France

CHU de Bordeaux, Groupe Sud

🇫🇷

Pessac, Gironde, France

CHU de Limoges

🇫🇷

Limoges, Haute Vienne, France

Clinique des Cèdres

🇫🇷

Cornebarrieu, Haute-Garonne, France

CHU de Toulouse - Hôpital Rangueil

🇫🇷

Toulouse, Haute-Garonne, France

HIA Percy Clamart

🇫🇷

Clamart, Hauts-de-Seine, France

Hôpital Marie Lannelongue

🇫🇷

Le Plessis-Robinson, Hauts-de-Seine, France

CHU de Rennes - Pontchaillou

🇫🇷

Rennes, Ille-et-Vilaine, France

CHU de Rennes - Hôpital Sud

🇫🇷

Rennes, Ille-et-Vilaine, France

Centre Hospitalier de Dax

🇫🇷

Dax, Landes, France

CHU d'Angers

🇫🇷

Angers, Maine-et-Loire, France

Institut Godinot

🇫🇷

Reims, Marne, France

CHU de Lille - Institut coeur poumon

🇫🇷

Lille, Nord, France

CHU de Lille - Hôpital Huriez

🇫🇷

Lille, Nord, France

CHU de Lille - Hôpital Jeanne de Flandre

🇫🇷

Lille, Nord, France

Clinique de la Plaine Santé

🇫🇷

Clermont-Ferrand, Puy-de-Dôme, France

CHU de Clermont-Ferrand

🇫🇷

Clermont-Ferrand, Puy-de-Dôme, France

Hôpital Edouard Herriot

🇫🇷

Lyon, Rhône, France

Centre Léon Bérard

🇫🇷

Lyon, Rhône, France

Hôpital mère-enfant (HCL)

🇫🇷

Bron, Rhône, France

Clinique de la Sauvegarde

🇫🇷

Lyon, Rhône, France

CHU de Rouen

🇫🇷

Rouen, Seine-Maritime, France

CHU d'Amiens

🇫🇷

Amiens, Somme, France

Clinique Victor Pauchet

🇫🇷

Amiens, Somme, France

Hôpital Nord Franche-Comté

🇫🇷

Trévenans, Territoire De Belfort, France

Hôpital NOVO - Site de Beaumont-sur-Oise

🇫🇷

Beaumont-sur-Oise, Val d'Oise, France

Hôpital Privé de la Chataigneraie

🇫🇷

Beaumont, Val d'Oise, France

Hôpital NOVO - Site de Pontoise

🇫🇷

Cergy-Pontoise, Val d'Oise, France

Centre Hospitalier Intercommunal de Villeneuve Saint Georges

🇫🇷

Villeneuve-Saint-Georges, Val-de-Marne, France

Sainte-Anne Military Teaching Hospital

🇫🇷

Toulon, Var, France

Centre Hospitalier Départemental de Vendée

🇫🇷

La Roche-sur-Yon, Vendée, France

Hôpital Lariboisière (AP-HP)

🇫🇷

Paris, France

Hôpital Saint Louis (AP-HP)

🇫🇷

Paris, France

Hôpital Trousseau (AP-HP)

🇫🇷

Paris, France

Hôpital La Pitié-Salpêtrière

🇫🇷

Paris, France

Hôpital Européen Georges Pompidou

🇫🇷

Paris, France

Hôpital Tenon (AP-HP)

🇫🇷

Paris, France

Groupe Hospitalier Diaconesses Croix Saint Simon

🇫🇷

Paris, France

Institut mutualiste Montsouris

🇫🇷

Paris, France

Hôpital Paul Brousse (AP-HP)

🇫🇷

Villejuif, France

CHU de Guadeloupe

🇬🇵

Pointe-à-Pitre, Guadeloupe

Centre Hospitalier de Brive-la-Gaillarde

🇫🇷

Brive-la-Gaillarde, Corrèze, France

Hôpital Nord (AP-HM)

🇫🇷

Marseille, Bouches-du-Rhône, France

Institut de Cancérologie de Lorraine

🇫🇷

Vandoeuvre les nancy, Meurthe-et-Moselle, France

CHU de Strasbourg - IHU

🇫🇷

Strasbourg, Bas-Rhin, France

CHU de Grenoble

🇫🇷

Grenoble, Isère, France

CHU de la Réunion

🇫🇷

Saint Denis, La Réunion, France

CHU de Bordeaux - Groupe hospitalier Pellegrin

🇫🇷

Bordeaux, Gironde, France

Centre Hospitalier Jacques Puel

🇫🇷

Rodez, Aveyron, France

Groupe Hospitalier Littoral Atlantique

🇫🇷

La Rochelle, Charente-Maritime, France

CHU de Nîmes

🇫🇷

Nîmes, Gard, France

Centre Hospitalier de Cannes

🇫🇷

Cannes, Alpes-Maritimes, France

CHU de Caen

🇫🇷

Caen, Calvados, France

Centre Hospitalier de Valence

🇫🇷

Valence, Drôme, France

Clinique la Croix du Sud

🇫🇷

Quint-Fonsegrives, Haute-Garonne, France

Centre Hospitalier de Lens

🇫🇷

Lens, Pas-de-Calais, France

Clinique Aguilera

🇫🇷

Biarritz, Pyrénées-Atlantiques, France

Institut Gustave Roussy

🇫🇷

Villejuif, Val-de-Marne, France

Hôpital Robert Schuman-Groupe UNEOS

🇫🇷

Vantoux, Vaucluse, France

Centre Hospitalier de Mayotte

🇾🇹

Mamoudzou, Mayotte

HIA Clermont Tonnerre

🇫🇷

Brest, Finistère, France

CHU Jean Minjoz

🇫🇷

Besançon, Doubs, France

Clinique mutualiste de Pessac

🇫🇷

Pessac, Gironde, France

Clinique de l'Union

🇫🇷

Saint-Jean, Haute-Garonne, France

Clinique mutualiste La Sagesse

🇫🇷

Rennes, Ille-et-Vilaine, France

Clinique de l'Archette

🇫🇷

Olivet, Loiret, France

Centre Oscar Lambret

🇫🇷

Lille, Nord, France

Centre Hospitalier Intercommunal Toulon - La Seyne sur Mer

🇫🇷

Toulon, Var, France

Centre Hospitalier de Cornouailles

🇫🇷

Quimper, Finistère, France

Centre Hospitalier de l'Agglomération Montargoise

🇫🇷

Amilly, Loiret, France

Groupe Hospitalier Bretagne Sud

🇫🇷

Lorient, Morbihan, France

Hôpital privé Arras les Bonnettes

🇫🇷

Arras, Pas-de-Calais, France

Centre Hospitalier Emile Roux

🇫🇷

Le Puy-en-Velay, Haute-Loire, France

Centre Hospitalier de Pau

🇫🇷

Pau, Pyrénées-Atlantiques, France

Centre Hospitalier Princesse Grace

🇲🇨

Monaco, Monaco

CHU de Lille - Hôpital Roger Salengro

🇫🇷

Lille, Nord, France

Centre Hospitalier Intercommunal Castres-Mazamet

🇫🇷

Castres, Tarn, France

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