Treatment of Complex PTSD

• Conditions: Complex PTSDPhase-based treatmentTrauma-focusedEMDRSTAIRComplexe PTSSTraumagerichtGefaseerde behandeling

• Registration Number: NL-OMON22074
• Lead Sponsor: niversity of Amsterdam UvAUniversity of Groningen RuG

Brief Summary

1. Study protocol.<br> 2. Article about the results of the RCT in which phase-based treatment versus directe trauma-focused treatment are compared in patients with Complex PTSD.<br> 3. Article about cost-effectiveness of both treatments.<br> 4. Article about predictors and moderators in the treatment of Complex PTSD.<br> 5. Article about possible predictors of worse outcome and drop-out in the treatment of Complex PTSD.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 122

Inclusion Criteria

In order to be eligible to participate in this study, a patient must meet all of the following criteria: a) meeting the criteria for PTSD, according to the Clinical-Administered PTSD Scale for DSM-5 (CAPS-5; Weathers et al., 2013), b) having symptoms of Complex PTSD, c) reporting a history of repeated physical and/or sexual abuse by a caretaker or person in authority during childhood (before the age of 18), d) being in the age between 18 and 65 years, e) giving an informed consent for study participation.

Exclusion Criteria

A patient who meets any of the following criteria will be excluded from participation in this study: a) insufficient competence in speaking the Dutch language, b) high risk of suicidality assessed by the BDI-II (Beck, Steer, and Brown, 1996), c) currently in treatment for PTSD, d) severe alcohol or drug dependence or abuse, e) IQ under 80, and f) victim of ongoing physical and/or sexual abuse.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of PTSD symptoms

Secondary Outcome Measures

Name	Time	Method
Secondary parameters include the presence of a PTSD diagnosis, severity of Complex PTSD symptoms and comorbid symptoms (i.e., anxiety, depression, general psychopathology), dissociation, health-related quality of life and drop out during treatment in both conditions.