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ltrasound guided regional anesthetic techniques in carotid surgery- Comparison of safety and effectiveness of deep cervical block (TCB), superficial cervical block (ICB) and perivascular block (PVB).

Not Applicable
Conditions
I65.2
Occlusion and stenosis of carotid artery
Registration Number
DRKS00016705
Lead Sponsor
niversitätsklinikum Carl Gustav Carus Dresden Klinik und Poliklinik für Anästhesiologie und Intensivtherapie
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

age > 18 years
-elective CEA surgery for treatment of ICA stenosis
-written informed consent

Exclusion Criteria

-history of anaphylactic reaction to local anesthetics
-local infection in the lateral cervical region
-presumed limitation of patients' compliance

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
As primary outcome, plasma levels of ropivacaine were measured with high performance liquid chromatography before, 5, 10, 30, 60, and 180 min after the injection of ropivacaine. Plasma concentration of ropivacaine were analyzed with a high performance liquid chromatography photodiode array detection system (Agilent 1100 series, Agilent Technologies, Waldbronn, Germany). For quantification, drug-free serum was spiked at five different concentrations of ropivacaine (100, 200, 500, 1000, 2000 ng/ml). Ropivacaine concentration was calculated using linear regression. The limit of quantification of the method was 100 ng/ml.
Secondary Outcome Measures
NameTimeMethod
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