NCT00771355终止不适用
In Vivo Imaging of Pigmentary Disorders by Reflectance Confocal Microscopy
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To describe characteristic features seen by confocal microscopy of several pigmentary disorders.
研究概览
简要总结
This is a pilot study to evaluate the findings of the Reflectance Confocal Microscopy when performed in cutaneous pigmentary disorders, such as vitiligo, melasma, post-inflammatory hyper-pigmentation and hypo-pigmentation. Confocal Microscopy is a recent diagnostic technique that has been used for observation of skin conditions that affect the superficial layers of the skin.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subjects 20-70 years of age.
- •Clinical diagnosis of vitiligo, melasma, post-inflammatory hypo or depigmentation or post-inflammatory hyperpigmentation.
- •Willing and able to understand and sign informed consent.
- •Able to complete study and comply with study procedures.
排除标准
- •Use of topical therapies such as corticosteroids, protopic, hydroquinone and azelaic acid within the past 2 months.
- •Use of light therapy such as narrow-band-UVB, PUVA or laser within the past 2 months.
- •Intake of medications that can cause pigmentary changes within the past year. Examples are:
- •Antimalarials (chloroquine, hydroxychloroquine)
- •Chemotherapeutics (bleomycin, busulfan, doxorubicin, daunorubicin, fluorouracil, cyclophosphamide, and carmustine)
- •Heavy metals (gold, silver, bismuth, and mercury)
- •Tetracyclines (including minocycline, doxycycline)
- •Amiodarone
- •Azidothymidine
- •Clofazimine
- •Clinically significant abnormal findings or conditions (other than the pigmentary disorder), which might, in the opinion of the Principal Investigator, interfere with study evaluations or pose a risk to subject safety during the study.
- •Subjects who are known to be pregnant or planning a pregnancy.
结局指标
主要结局
To describe characteristic features seen by confocal microscopy of several pigmentary disorders.
时间窗: study visit
次要结局
未报告次要终点
研究者
研究点 (1)
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