NL-OMON48861已完成不适用
The effect of quinine on food intake: oral sham feeding versus intragastric delivery - Quinine and food intake
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Based on medical history and previous examination, no gastrointestinal
- •complaints can be defined.
- •- Age from 18 until 65 years. This study will include healthy adult subjects
- •(male and female).
- •- BMI from 18 until 25 kg/m2
- •- Bodyweight stable over at least the last 6 months (up until 5% weight change
排除标准
- •- History of severe cardiovascular, respiratory, urogenital, gastrointestinal/
- •hepatic, hematological/immunologic, HEENT (head, ears, eyes, nose, throat),
- •dermatological/connective tissue, musculoskeletal, metabolic/nutritional,
- •endocrine, neurological/psychiatric diseases, allergy, major surgery and/or
- •laboratory assessments which might limit participation in or completion of the
- •study protocol. The severity of the disease (major interference with the
- •execution of the experiment or potential influence on the study outcomes) will
- •be decided by the principal investigator.
- •- Use of medication that can influence study end-points (to be discussed by
- •medical doctor and principal investigator), including vitamin supplementation,
- •within 14 days prior to testing
- •- Administration of investigational drugs or participation in any scientific
- •intervention study which may interfere with this study (to be decided by the
- •principle investigator), in the 180 days prior to the study
- •- Major abdominal surgery interfering with gastrointestinal function
- •(uncomplicated appendectomy and hysterectomy allowed, and other surgery upon
- •judgement of medical doctor and principle investigator)
- •- Dieting (medically prescribed, vegetarian, diabetic, macrobiological,
- •biological dynamic)
- •- Unwillingness to eat lasagna bolognese meal
- •- Pregnancy, lactation
- •- Excessive alcohol consumption (>20 alcoholic consumptions per week)
- •- Non-tasters of bitter
研究者
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